Acid peptic disease is a state of imbalance of Acid peptic secretion and protective
mechanism of gastric mucosa.
Mucus secretion by mucous cells protects the gastric mucosa. (Inner Layer)
Acid secretion has 2 phases – Basal and Stimulated.
Basal phase is also called the interdigestive phase present, when the stomach is
empty, Basal secretion is maximum during night, is controlled by vagus, local
histamine stimulation and affected by emotions.
Normally basal secretion is rich in mucus, small in pepsin & almost no acid.
Emotions like worry increase basal acid secretion by vagal stimulation. ✓ Stimulated
phase is when food is present in the stomach. It is mediated by vagus, histamine,
and gastrin.
Histamine is produced by special cells in the stomach and gastrin is produced by
gastric cells near the pyloric antrum. Stimulated phase secretion is rich in acid,
pepsin & mucus
How does stress induce APD?
Stress mainly, extensive burns & emotions, lead to high levels of ACTH and
corticotropin
secreted by pituitary & cortisol secreted by adrenal cortex. These two leads to
decrease in
mucus secretion. (This action is mediated by inhibiting the release of Arachidonic
acid from
membrane lipids .Physiologically the Arachidonic acid is converted by Cyclooxygenase
(COX 1)
into prostaglandins which participate in mucus production by gastric mucosa. NSAIDS
inhibit
COX 1 & 2 to minimize the production of inflammatory prostaglandins, to exhibit
their
effect, but while doing so damage the gastric mucosa)
Stress leads to hypothalamic stimulation of vagal activity causing increase in basal
acid
secretion & some of the stimulated one. Emotional stimuli often lead to increase in
basal
(inter digestive)secretion by the Cephalic pathway of vagal stimulation. This is
rich in
pepsin & acid.
(Gastric secretion occurs in three phases, Cephalic, Gastric & Intestinal. Cephalic
is the
one which occurs before food enters the stomach. Sight, smell, taste & thought of
food are
the neurogenic signals, which originate in cerebral cortex & appetite centers of
amygdala &
hypothalamus & are transmitted through vagi to stomach)
Thus both factors together lead to an imbalance between acid peptic secretion and mucus
protection leading to acid peptic disease
Standard program changes breathing pattern, which corrects autonomic arousal.
Conscious Abdominal Breathing increases the strength of diaphragm. Esophagus enters the
abdominal cavity by passing through the right crus of diaphragm. It is compressed during
expiration (refer to Anatomy Vol 2 - 30.6) preventing the regurgitation of contents of
stomach into esophagus. (GERD
Gastro-esophageal reflux disease)
Pranayam sequence helps in emotional stability & cognitive corrections leading to less
incidents of autonomic arousals
Benefits of Medical Yoga Therapy
Medical yoga therapy helps in stress management.
Medical yoga therapy helps in dietary discipline.
Medical yoga therapy improves sleep patterns.
GNOSIS MEDICAL YOGA FOUNDATION REG NO E-8508/PUNE UNDER MAHARASHTRA PUBLIC TRUST ACT 1950 ( 80 G certified)